Corticosteroids for managing tuberculous meningitis

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Corticosteroids for managing tuberculous meningitis

BACKGROUND Tuberculous meningitis, a serious form of tuberculosis that affects the meninges covering the brain and spinal cord, is associated with high mortality and disability among survivors. Corticosteroids have been used as an adjunct to antituberculous drugs to improve the outcome, but their role is controversial. OBJECTIVES To evaluate the effects of corticosteroids as an adjunct to ant...

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Evaluation of corticosteroids in treatment of tuberculous meningitis.

98 patients with tuberculous meningitis were studied with a view to assessing the value of steroids as an adjuvant to antitubercular drugs. The patients were divided into three groups irrespective of the clinical stage of the disease. One group received antitubercular drugs alone, the second oral prednisolone, and the third intrathecal steroids, in addition to the antitubercular drugs. There wa...

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Corticosteroids for tuberculous pleurisy

BACKGROUND Corticosteroids used in addition to antituberculous therapy have been reported to benefit people with tuberculous pleurisy. However, research findings are inconsistent and raise doubt as to whether such treatment is worthwhile. There is also concern regarding the potential adverse effects of corticosteroids, especially in HIV-positive people. OBJECTIVES To evaluate the effects of a...

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Tuberculous Meningitis

This is a brief review of the cases of tuberculous meningitis treated at Ham Green Hospital with streptomycin. Since 1948, seventy-seven cases have been admitted and of these thirty-five (45 per cent) are still living. For the purpose of this review seventeen cases are excluded?eight because they have been admitted too recently and nine, the earliest cases, either because they received quite in...

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Corticosteroids for acute bacterial meningitis.

Death and long-term disabilities are common outcomes of acute bacterial meningitis, especially in developing countries, even when highly effective antibiotic therapy is given. Therefore, improvement in the outcomes of acute bacterial meningitis is unlikely to come from developments in chemotherapy but rather from measures that alleviate the damage done before the causative bacteria are killed. ...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2016

ISSN: 1465-1858

DOI: 10.1002/14651858.cd002244.pub4